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Olivier Lortholary Selected Research

Flucytosine (Ancobon)

1/2022Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.
1/2022Access to flucytosine for the treatment of HIV-associated cryptococcal meningitis in Africa.
1/2020Addition of Flucytosine to Fluconazole for the Treatment of Cryptococcal Meningitis in Africa: A Multicountry Cost-effectiveness Analysis.
1/2019Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries.
1/2018Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.
1/2016Acquired Flucytosine Resistance during Combination Therapy with Caspofungin and Flucytosine for Candida glabrata Cystitis.
11/2013Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal.
2/2010Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america.
8/2008Major role for amphotericin B-flucytosine combination in severe cryptococcosis.
1/2006Efficacy of amphotericin B in combination with flucytosine against flucytosine-susceptible or flucytosine-resistant isolates of Cryptococcus neoformans during disseminated murine cryptococcosis.

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Olivier Lortholary Research Topics

Disease

74Infections
06/2022 - 12/2002
22Aspergillosis
12/2021 - 08/2002
20Cryptococcosis
01/2018 - 02/2004
15Cryptococcal Meningitis
01/2022 - 08/2007
14Neoplasms (Cancer)
12/2021 - 02/2003
14Mycoses (Diseases, Fungus)
06/2020 - 06/2008
12Candidiasis (Moniliasis)
03/2021 - 08/2004
12Mastocytosis
09/2019 - 10/2005
12Mucormycosis
01/2018 - 02/2006
10Immune Reconstitution Inflammatory Syndrome
10/2019 - 07/2005
9Invasive Fungal Infections
11/2021 - 06/2008
9Diabetes Mellitus
03/2021 - 09/2009
9Hematologic Neoplasms (Hematological Malignancy)
11/2020 - 08/2006
8Invasive Candidiasis
01/2022 - 11/2006
8Fungemia
01/2021 - 10/2005
8Acquired Immunodeficiency Syndrome (AIDS)
01/2016 - 02/2004
7Chronic Granulomatous Disease
01/2021 - 03/2011
7Systemic Mastocytosis
11/2017 - 12/2002
7HIV Infections (HIV Infection)
03/2016 - 02/2004
6Nocardia Infections
01/2022 - 01/2016
6Communicable Diseases (Infectious Diseases)
01/2022 - 08/2004
6Candidemia
01/2021 - 01/2009
6Meningoencephalitis
11/2013 - 02/2007
5Tuberculosis (Tuberculoses)
01/2022 - 07/2014
5Sepsis (Septicemia)
05/2021 - 10/2008
5Meningitis
03/2021 - 01/2019
5Neutropenia
11/2020 - 08/2004
5Lymphopenia (Lymphocytopenia)
01/2015 - 05/2010
4Body Weight (Weight, Body)
01/2022 - 08/2002
4Histoplasmosis
01/2021 - 01/2006
4Bacterial Infections (Bacterial Infection)
01/2021 - 07/2008
4Cross Infection (Nosocomial Infection)
03/2016 - 01/2009
4Hidradenitis Suppurativa
02/2016 - 02/2011
4Pneumonia (Pneumonitis)
09/2013 - 02/2010
4Zygomycosis (Phycomycosis)
02/2013 - 04/2008
4Renal Insufficiency (Renal Failure)
09/2010 - 03/2007
3Abscess
03/2021 - 07/2004
3Invasive Pulmonary Aspergillosis
05/2020 - 04/2005
3Bronchiectasis
12/2019 - 03/2012
3Endocarditis
01/2018 - 07/2013
3Wounds and Injuries (Trauma)
10/2017 - 08/2013
3Arthritis (Polyarthritis)
04/2017 - 01/2006
3Cellulitis
07/2015 - 12/2004

Drug/Important Bio-Agent (IBA)

17AntigensIBA
12/2021 - 04/2006
17Voriconazole (Vfend)FDA LinkGeneric
01/2018 - 08/2002
16Amphotericin B (Amphotericin)FDA LinkGeneric
01/2020 - 08/2002
15Anti-Bacterial Agents (Antibiotics)IBA
06/2022 - 01/2004
12Pharmaceutical PreparationsIBA
03/2021 - 10/2008
11Fluconazole (Zonal)FDA LinkGeneric
01/2022 - 10/2005
10Flucytosine (Ancobon)FDA Link
01/2022 - 01/2006
10liposomal amphotericin BFDA Link
01/2022 - 05/2007
9Antifungal AgentsIBA
01/2021 - 08/2004
8AzolesIBA
01/2021 - 08/2004
8Adrenal Cortex Hormones (Corticosteroids)IBA
11/2020 - 03/2008
8posaconazoleFDA Link
11/2019 - 12/2009
8Caspofungin (Cancidas)FDA Link
01/2017 - 11/2006
7Immunoglobulins (Immunoglobulin)IBA
01/2021 - 01/2004
6EchinocandinsIBA
01/2022 - 01/2012
6Carbapenems (Carbapenem Antibiotics)IBA
05/2021 - 02/2009
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2021 - 09/2013
6Biomarkers (Surrogate Marker)IBA
04/2017 - 02/2012
6Biological ProductsIBA
11/2016 - 09/2009
5Immunosuppressive Agents (Immunosuppressants)IBA
12/2021 - 03/2007
5SteroidsIBA
01/2018 - 10/2012
5VaccinesIBA
06/2017 - 11/2008
4Proteins (Proteins, Gene)FDA Link
01/2022 - 10/2013
4deoxycholate drug combination amphotericin BIBA
01/2022 - 08/2002
4galactomannanIBA
12/2021 - 07/2012
4Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric
08/2021 - 10/2015
4DNA (Deoxyribonucleic Acid)IBA
01/2021 - 01/2004
4STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
06/2020 - 02/2012
4Interleukin-17 (Interleukin 17)IBA
01/2020 - 08/2011
4isavuconazoleIBA
10/2019 - 02/2016
4Thalidomide (Thalomid)FDA Link
02/2017 - 10/2012
4Calcineurin InhibitorsIBA
01/2016 - 03/2007
4LipidsIBA
02/2012 - 11/2005
3Immunoglobulin G (IgG)IBA
01/2021 - 12/2002
3CytokinesIBA
12/2020 - 01/2013
3TriazolesIBA
01/2018 - 10/2014
3Tacrolimus (Prograf)FDA LinkGeneric
12/2017 - 09/2009
3Phosphotransferases (Kinase)IBA
11/2017 - 02/2003
3masitinibIBA
11/2017 - 12/2010
3midostaurinIBA
01/2017 - 01/2014
3Rifampin (Rifampicin)FDA LinkGeneric
01/2016 - 02/2011
3NADPH Oxidases (NAD(P)H oxidase)IBA
12/2013 - 03/2011
3Itraconazole (Sporanox)FDA LinkGeneric
11/2013 - 12/2011

Therapy/Procedure

76Therapeutics
06/2022 - 08/2002
15Transplantation
01/2022 - 09/2009
15Highly Active Antiretroviral Therapy (HAART)
12/2015 - 02/2004
10Organ Transplantation
06/2022 - 07/2011
10Drug Therapy (Chemotherapy)
12/2021 - 03/2010
6Stem Cell Transplantation
05/2020 - 06/2011
5Catheters
01/2018 - 05/2007
4Biological Therapy
12/2020 - 09/2013
4Central Venous Catheters
10/2019 - 08/2010
4Liver Transplantation
11/2010 - 11/2006
4Critical Care (Surgical Intensive Care)
01/2010 - 08/2004
3Duration of Therapy
05/2020 - 10/2005
3Bone Marrow Transplantation (Transplantation, Bone Marrow)
05/2020 - 11/2006
3Hematopoietic Stem Cell Transplantation
01/2019 - 02/2010